Profhilo Structura is an innovative injectable treatment specifically designed to restore superficial fat to its natural position while counteracting the gradual loss of tissue that occurs with aging. By addressing age-related concerns such as pronounced hollows and changes in facial contours due to midface fat depletion, Profhilo Structura effectively lifts, sculpts, and enhances facial definition. This cutting-edge treatment works to rejuvenate the skin from within, promoting a more youthful and harmonized appearance.
Ageing and Profhilo
Ageing isn’t just about the skin — it goes deeper than what we see. As we get older, a series of changes occur not only in the skin but in the layers beneath it: superficial fat, muscle, deep fat, and even the bone structure. These shifts don’t all happen at once — they occur gradually, in different areas of the face, and at different times depending on genetics, lifestyle, and ethnicity. That’s why it’s so important to choose treatments that go beyond the surface. To truly restore a more youthful appearance, we need to address the entire facial structure — not just fine lines and wrinkles.
PROFHILO® is indicated for tissue remodelling and improving skin laxity on the face and neck. It is an injectable treatment based on patented NAHYCO® Hybrid Technology, a chemical-free (NO BDDE), thermal production process, that makes it possible to obtain Stabilised Hybrid Cooperative Complexes (HCC), which combines Ultrapure Hyaluronic Acid with both low and high molecular weight in high concentration, produced with a unique and innovative thermal production process patented by IBSA, the NAHYCO® Technology. The NAHYCO® Hybrid Technology has made it possible to obtain and introduce an unrivalled, high concentration of hyaluronic acid, giving the product higher resistance to degradation in comparison to the simple linear HA.

Profhilo Structura is one of the few non-surgical treatments designed to support these deeper layers, helping to restore volume and firmness where the face needs it most, without changing your natural features.
As we get older, a series of changes occur gradually, in different areas of the face.
Profhilo vs Profhilo Structura: Which Treatment Is Right for You?
More and more of my clients — particularly women in their 40s, 50s, and beyond — are asking about non-surgical ways to rejuvenate their appearance while still looking natural and feeling like themselves.
But now there’s a powerful new option available: Profhilo Structura.
Structura is the latest innovation from the same trusted manufacturer as Profhilo. It’s designed to go deeper, working in the superficial fat layer of the face to gently reshape and lift — without the added volume of traditional fillers. If you’ve noticed sagging in the cheeks, jawline or lower face, but want to avoid looking “done” or overfilled, this could be the perfect treatment for you.

Many of my patients at Flawless Aesthetic Clinic are already seeing impressive results with this next-generation injectable — especially those seeking a natural alternative to dermal fillers.
Profhilo vs Profhilo Structura at a glance
Profhilo is mainly used when the priority is skin quality — hydration, texture and elasticity. Profhilo Structura is designed to work in the superficial fat layer when loss of support or facial deflation is part of the concern.
Neither treatment is automatically “better”. The more useful question is which tissue change is contributing most to what you see in the mirror — and whether one treatment, both at different stages, or another approach is the best fit.
What Is Profhilo — and Why Is It So Popular?
If you’ve ever searched for a treatment to refresh tired-looking skin without changing your face shape, you’ve likely come across Profhilo. It’s one of the most requested injectables in my Wimbledon clinic — and with good reason.
Unlike traditional fillers or anti wrinkle injections, Profhilo is a pure hyaluronic acid (HA) skin booster. Rather than adding volume or freezing movement, it works by deeply hydrating and stimulating collagen and elastin — the key building blocks of youthful, elastic skin.
What Makes Profhilo Unique?
- One of the highest concentrations of HA on the market
- Bio-remodelling action — it reprogrammes skin cells to repair and regenerate
- Injected into specific “BAP” points (Bio Aesthetic Points) for optimal spread
- Suitable for face, neck, hands, and décolletage
- Ideal for men and women in their 30s and beyond
This treatment has gained a devoted following because it delivers visible improvements in tone, hydration, texture, and elasticity — all with no downtime and no artificial look.
Where Profhilo Works Best
- Fine lines and crepey skin
- Dull or dehydrated complexions
- Mild sagging in the face, neck or chest
- Tired skin that needs an overall glow boost
It’s often the first injectable I recommend to clients in their 30s, 40s and 50s who want a subtle refresh and have concerns about an altered look.
Would you like to know whether Profhilo or Profhilo Structura — or even a combination of both — is the right choice for your skin?


